Aviva Systems Triiodothyronine (T3) Elisa Kit (Human)

Description: Description of target: ;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: 0.2 ng/ml

Description: Description of target: Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 5.9 pg/mL

Description: Description of target: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).By similarity2 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.1"ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28."_x005F_x005F_x000D_Hutloff A., Dittrich A.M., Beier K.C., Eljaschewitsch B., Kraft R., Anagnostopoulos I., Kroczek R.A._x005F_x005F_x000D_Nature 397:263-266(1999) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE (ISOFORM 1), PROTEIN SEQUENCE OF 192-198, FUNCTION, SUBUNIT, TISSUE SPECIFICITY.Ref.8"Induction, binding specificity and function of human ICOS."_x005F_x005F_x000D_Beier K.C., Hutloff A., Dittrich A.M., Heuck C., Rauch A., Buechner K., Ludewig B., Ochs H.D., Mages H.W., Kroczek R.A._x005F_x005F_x000D_Eur. J. Immunol. 30:3707-3717(2000) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, GLYCOSYLATION, SUBUNIT, INDUCTION, TISSUE SPECIFICITY. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 5.8 pg/mL

Description: Description of target: ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 6.4 pg/mL

Description: Description of target: Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration.2 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.17"CD155/PVR plays a key role in cell motility during tumor cell invasion and migration."_x005F_x005F_x000D_Sloan K.E., Eustace B.K., Stewart J.K., Zehetmeier C., Torella C., Simeone M., Roy J.E., Unger C., Louis D.N., Ilag L.L., Jay D.G._x005F_x005F_x000D_BMC Cancer 4:73-73(2004) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION.Ref.21"PVR (CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis."_x005F_x005F_x000D_Pende D., Bottino C., Castriconi R., Cantoni C., Marcenaro S., Rivera P., Spaggiari G.M., Dondero A., Carnemolla B., Reymond N., Mingari M.C., Lopez M., Moretta L., Moretta A._x005F_x005F_x000D_Mol. Immunol. 42:463-469(2005) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION. (Microbial infection) Acts as a receptor for poliovirus. May play a role in axonal transport of poliovirus, by targeting virion-PVR-containing endocytic vesicles to the microtubular network through interaction with DYNLT1. This interaction would drive the virus-containing vesicle to the axonal retrograde transport (PubMed:2538245). Acts as a receptor for pseudorabies virus (PubMed:9616127). Is prevented to reach cell surface upon infection by human cytomegalovirus /HHV-5, presumably to escape immune recognition of infected cell by NK cells (PubMed:15640804).3 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.1"Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily."_x005F_x005F_x000D_Mendelsohn C.L., Wimmer E., Racaniello V.R._x005F_x005F_x000D_Cell 56:855-865(1989) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION (MICROBIAL INFECTION), INTERACTION WITH POLIOVIRUS CAPSID PROTEINS.Ref.9"Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor."_x005F_x005F_x000D_Geraghty R.J., Krummenacher C., Cohen G.H., Eisenberg R.J., Spear P.G._x005F_x005F_x000D_Science 280:1618-1620(1998) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION (MICROBIAL INFECTION), INTERACTION WITH PSEUDORAVIES VIRUS GD PROTEIN.Ref.22"Downregulation of natural killer cell-activating ligand CD155 by human cytomegalovirus UL141."_x005F_x005F_x000D_Tomasec P., Wang E.C., Davison A.J., Vojtesek B., Armstrong M., Griffin C., McSharry B.P., Morris R.J., Llewellyn-Lacey S., Rickards C., Nomoto A., Sinzger C., Wilkinson G.W._x005F_x005F_x000D_Nat. Immunol. 6:181-188(2005) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION (MICROBIAL INFECTION), INTERACTION WITH HHV-5 UL141. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 6.0 pg/mL

Description: Description of target: ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 6.5 pg/mL

Description: Description of target: Plays a role in angiogenesis and possibly in the development of tumors. May be a housekeeping chemokine regulating recruitment of nonactivated blood monocytes and immature dendritic cells into tissues. May play a role in the innate defense against infections.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 5.9 pg/mL

Description: Description of target: Involved in nervous system development and function. Promote neuronal excitability by elevating the voltage dependence of neuronal sodium channel SCN8A fast inactivation.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 5.6 pg/mL

Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Triiodothyronine (T3) in serum, plasma and other biological fluids.

Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Triiodothyronine (T3) in serum, plasma and other biological fluids.

Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Triiodothyronine (T3) in serum, plasma and other biological fluids.

Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Triiodothyronine (T3) in serum, plasma and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of General Triiodothyronine (T3) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.

Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Chicken;Sensitivity: 0.094 ng/ml

Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Cattle;Sensitivity: 0.094 ng/ml

Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Rattus;Sensitivity: 0.094 ng/ml