Altered electroencephalographic networks in developmental dyslexia after remedial training: a prospective case-control study

Electroencephalographic studies using a graphical theoretical analysis found aberrations in functional connectivity in children with development dyslexia. However, how training with visual tasks can change the functional connectivity of the Semantic Dyslexia Development Network is still unclear. We have sought differences in local and global topological properties of functional networks between 21 healthy controls and 22 dyslexic children (8-9 years old) before and after training with visual tasks in this prospective case study. The expanded minimum tree method was used to build the brain networks of subjects in several electroencephalographic frequency ranges during a visual task of Word / Pseudoword discrimination.

We found group differences in the Theta, Alpha, Beta and Gamma bands for four graphical measurements suggesting a more integrated network topology in the dyslexic before training compared to controls. After training, the topology of the network of dyslexic children had become more separated and similar to that of controls. In the strips θ, α and β1-frequencies, compared to the controls, the pre-coaching dyslexics presented a reduced degree and a centrality between the anterior left and parietal temporal regions. The simultaneous appearance in the left hemisphere of temporal and parietal cortex concentries (α, β1), temporal and upper (θ, α), parietal and ocipitotemporal corretips (β1), identified in the normally developing children’s networks n ‘was not present in the cerebral networks of the dyslexic.

 

After training, the Hub distribution for dyslexic in the Theta and Beta1 bands had become similar to that of controls. In summary, our results indicate a less effective network configuration in the dyslexus compared to a more optimal world organization of controls. This is the first study to study the topological organization of functional brain networks of Bulgarian dyslexic children. The approval of the study was obtained from the Ethics Committee of the Institute of Neurobiology and the Institute of Population and Human Studies.

 

Thermostable enzymes and polysaccharides produced by thermophilic bacteria isolated from Bulgarian hot springs

Thermozatable enzymes (thermozymes) have been recognized as compounds extremely extremely important biotechnology in different industrial zones. Recently, exopolysaccharides (EPSS) synthesized by thermophiles have become an object of increasing the interest of the research because of their unique properties adapted to certain specific industrial needs. The thermophilic producers of biotechnologically valuable enzymes and new EPS have been isolated by our group of Bulgarian thermal springs with a diverse geotectonic origin and different properties of water.

Laboratory reactor processes for their production have been developed in batch and continuous crops. Some of the synthesized thermostable enzymes were among the first described in their groups, for example, the known single thermostable gellan lyase that demonstrated a specific activity superior to that of mesophilic enzymes. Isolated by US Thermostable Xylanase was able to degrade more than 60% Beechwood Xylan in a coprocess with an archae β-xylosidase. The lipase purified by us was active between 55 and 90 ° C with an optimum at 75-80 ° C in a large pH range. It was able to degrade a wide range of substrates. Isans Bulgarian warm sources synthesized EPS with a new composition and high thermostability. Thus, Bulgarian hot springs are a wide range of thermophilic producers of new enzymes and EPA with a large number of biotechnology applications.

 Altered electroencephalographic networks in developmental dyslexia after remedial training: a prospective case-control study
Altered electroencephalographic networks in developmental dyslexia after remedial training: a prospective case-control study

Potential of the enzymatic ligninolytic complex produced by mushrooms of white rot from isolated genus of the Bulgarian forest floor

Due to the crucial role of ligninolytic enzymes in a variety of industrial processes, the demand for a new effective producer has consistently increased. In addition, information on the synthesis of the enzyme by autochatonous fungus strains are very rarely found. Two fungal strains producing ligninolytic enzymes have been isolated from Bulgarian Forest Floor. They have been identified as trogii and T. hirsuta trameters. These two strains were evaluated for their enzymatic activities, laccase (lake), lignin peroxidase (LIP) and peroxidase (MNP) dependent on the culture filtrate according to the temperature and type of nutrient medium. T. trogii has been selected as a better producer of ligninolytic enzymes. The production process has also been improved by optimizing a number of parameters such as incubation time, the type of cultivation, the average volume ratio / air, inoculum size and the addition of inducers .

The maximum enzyme activities synthesized by T. trogii were detected as 11100 U / L for tray, 2.5 U / L for lip and 4.5 U / L for MNP after 14 days of incubation at 25 ° C under conditions Static, average volume ratio / air 1: 6 and 3 plugs as inoculum. Among the supplements tested, 5% glycerol increases the activity of the gap to a large extent. The addition of 1% VERATRLER alcohol had a positive effect on the MNP. Traditional fermented dairy products have been prepared since the ancient period by various civilizations. Despite their long history, their popularity and nutrient and healthy value, the acceleration and industrialization of food production lead to an increase in the diversity of fermented dairy products in the Balkan peninsula.

MBHA resin

20-abx095143
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 g
  • 1 kg
  • 250 g
  • 25 g
  • 500 g

Wang resin

20-abx095148
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 g
  • 250 g
  • 500 g

Wang Resin

A6776-100000 100 g
EUR 104
Description: Wang Resin

Wang Resin

A6776-25000 25 g
EUR 52
Description: Wang Resin

MBHA Resin

5-08203 25g
EUR 184.28

MBHA Resin

5-08204 100g
EUR 546

MBHA Resin

5-08205 25g
EUR 184.28

MBHA Resin

5-08206 100g
EUR 546

Wang Resin

5-08227 25g
EUR 66.89

Wang Resin

5-08228 100g
EUR 197.93

MBHA Resin

abx095143-100l 100 µl
EUR 262.5

MBHA Resin

abx095143-1ml 1 ml
EUR 1062.5

MBHA Resin

abx095143-200l 200 µl
EUR 587.5

Wang Resin

abx095148-100l 100 µl
EUR 187.5

Wang Resin

abx095148-1ml 1 ml
EUR 625

Wang Resin

abx095148-200l 200 µl
EUR 337.5

MSNT Resin

abx095152-100l 100 µl
EUR 250

MSNT Resin

abx095152-1ml 1 ml
EUR 1575

MSNT Resin

abx095152-200l 200 µl
EUR 625

Merrifield resin

20-abx095147
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 g
  • 250 g
  • 500 g

Merrifield Resin

5-08215 25g
EUR 31.4

Merrifield Resin

5-08216 100g
EUR 91.46

Merrifield Resin

5-08217 25g
EUR 31.4

Merrifield Resin

5-08218 100g
EUR 91.46

Merrifield Resin

abx095147-100l 100 µl
EUR 225

Merrifield Resin

abx095147-1ml 1 ml
EUR 625

Merrifield Resin

abx095147-200l 200 µl
EUR 387.5

Epon® Resin 1001F

24305-500 500g
EUR 103
Description: 25036-25-3

Podophyllum resin

464424 10.0mg Ask for price

Polystyrene Resin

5-08189 25g
EUR 36.86

Polystyrene Resin

5-08190 100g
EUR 113.3

PEG 4000 Resin

16861-250 250g
EUR 55

Epon® Resin 828

02334-500 500g
EUR 146
Description: 25068-38-6

DHP HM Resin

A6789-100000 100 g
EUR 616.8
Description: DHP HM Resin

DHP HM Resin

A6789-25000 25 g
EUR 243.6
Description: DHP HM Resin

Ni-NTA Resin

20-abx098108
  • Ask for price
  • Ask for price
  • 25 ml
  • 5 ml

Ni-IDA Resin

20-abx098109
  • Ask for price
  • Ask for price
  • 25 ml
  • 5 ml

MP-EDC resin

20-abx095129
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 g
  • 25 g
  • 5 g

MP-TMT resin

20-abx095142
  • Ask for price
  • Ask for price
  • 100 g
  • 25 g

MP-TMT Resin

abx095142-100l 100 µl
EUR 187.5

MP-TMT Resin

abx095142-1ml 1 ml
EUR 675

MP-TMT Resin

abx095142-200l 200 µl
EUR 300

Ni-NTA Resin

abx098108-100l 100 µl
EUR 300

Ni-NTA Resin

abx098108-1ml 1 ml Ask for price

Ni-NTA Resin

abx098108-200l 200 µl
EUR 625

Ni-IDA Resin

abx098109-100l 100 µl
EUR 287.5

Ni-IDA Resin

abx098109-1ml 1 ml Ask for price

Ni-IDA Resin

abx098109-200l 200 µl
EUR 562.5

Ramage AM Resin

abx095151-100l 100 µl
EUR 250

Ramage AM Resin

abx095151-1ml 1 ml
EUR 1412.5

Ramage AM Resin

abx095151-200l 200 µl
EUR 537.5

Protein A Resin

abx098111-5ml 5 ml
EUR 477.6

Protein G Resin

abx098112-5ml 5 ml
EUR 526.8

MP-TEMPO resin

20-abx095130
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 g
  • 25 g
  • 5 g

Rink Amide Resin

A6576-100000 100 g
EUR 1136.4
Description: Rink resin is originally developed for SPS of peptide amides. Now the scope of its application is extended from carboxylic amides to the immobilization of amines, substituted amides.

Rink Amide Resin

A6576-25000 25 g
EUR 172
Description: SPS of peptide amides

Weinreb AM Resin

5-08231 25g
EUR 393.12

Weinreb AM Resin

5-08232 100g
EUR 1182.09

Protein A Resin

abx098111-100l 100 µl
EUR 487.5

Protein A Resin

abx098111-1ml 1 ml Ask for price

Protein A Resin

abx098111-200l 200 µl Ask for price

Protein G Resin

abx098112-100l 100 µl
EUR 550

Protein G Resin

abx098112-1ml 1 ml Ask for price

Protein G Resin

abx098112-200l 200 µl Ask for price

Sieber Amide Resin

5-08225 5g
EUR 232.05

Sieber Amide Resin

5-08226 25g
EUR 819

GST-Sefinose Resin

BSP031 5ml
EUR 174.84

GST-Sefinose Resin

BSP031-1 25ml
EUR 498.48

MP-Carbonate resin

20-abx095138
  • Ask for price
  • Ask for price
  • 100 g
  • 25 g

Nickel Agarose Resin

abx291340-100g 100 µg
EUR 6550

Nickel Agarose Resin

abx291340-20g 20 µg
EUR 562.5

Nickel Agarose Resin

abx291340-50g 50 µg
EUR 1787.5

Biotin Agarose Resin

abx291342-100g 100 µg Ask for price

Biotin Agarose Resin

abx291342-20g 20 µg
EUR 412.5

Biotin Agarose Resin

abx291342-50g 50 µg
EUR 687.5

MP-Carbonate Resin

abx095138-100l 100 µl
EUR 175

MP-Carbonate Resin

abx095138-1ml 1 ml
EUR 550

MP-Carbonate Resin

abx095138-200l 200 µl
EUR 262.5

Biotin Agarose Resin

4BCL-BI-10 10 ml
EUR 466.21

Biotin Agarose Resin

4BCL-BI-5 5 ml
EUR 245.37

MP-Aminomethyl resin

20-abx095132
  • Ask for price
  • Ask for price
  • 100 g
  • 25 g

MP-Thiosulfate resin

20-abx095140
  • Ask for price
  • Ask for price
  • 100 g
  • 25 g

MP-Thiosulfate Resin

abx095140-100l 100 µl
EUR 175

MP-Thiosulfate Resin

abx095140-1ml 1 ml
EUR 550

MP-Thiosulfate Resin

abx095140-200l 200 µl
EUR 262.5

Bromoacetyl resin (200-400 mesh)

D-2555.0001 1.0g
EUR 166.8

Bromoacetyl resin (200-400 mesh)

D-2555.0005 5.0g
EUR 529.2

Bromoacetyl resin (200-400 mesh)

4029092.0005 5 g
EUR 317.94

MP-Acetylacetone resin

20-abx095133
  • Ask for price
  • Ask for price
  • 100 g
  • 25 g

MP-Mercaptomethyl resin

abx095141-100g 100 g
EUR 610.8

Glutathione Agarose Resin

DS0819-25ML 1 unit
EUR 288.31
Description: Glutathione Agarose Resin

Glutathione Agarose Resin

DS0819-5ML 1 unit
EUR 64.11
Description: Glutathione Agarose Resin

Glutathione Agarose Resin

abx291341-100g 100 µg Ask for price

Glutathione Agarose Resin

abx291341-20g 20 µg
EUR 325

Glutathione Agarose Resin

abx291341-50g 50 µg
EUR 1700

MP-Mercaptomethyl Resin

abx095141-100l 100 µl
EUR 175

MP-Mercaptomethyl Resin

abx095141-1ml 1 ml
EUR 600

MP-Mercaptomethyl Resin

abx095141-200l 200 µl
EUR 275

Glutathione Agarose Resin

4B-GLU-10 10 ml
EUR 178.66

Glutathione Agarose Resin

4B-GLU-100 100 ml
EUR 1284.3

Rink Amide AM resin

20-abx095146
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 g
  • 1 kg
  • 250 g
  • 25 g
  • 500 g

Rink Amide AM Resin

abx095146-100l 100 µl
EUR 187.5

Rink Amide AM Resin

abx095146-1ml 1 ml
EUR 1025

Rink Amide AM Resin

abx095146-200l 200 µl
EUR 387.5

MP-Piperazinomethyl resin

20-abx095134
  • Ask for price
  • Ask for price
  • 100 g
  • 25 g

MP-Morpholinomethyl resin

20-abx095139
  • Ask for price
  • Ask for price
  • 100 g
  • 25 g

MP-Piperazinomethyl Resin

abx095134-100l 100 µl
EUR 237.5

MP-Piperazinomethyl Resin

abx095134-1ml 1 ml Ask for price

MP-Piperazinomethyl Resin

abx095134-200l 200 µl
EUR 500

MP-Morpholinomethyl Resin

abx095139-100l 100 µl
EUR 175

MP-Morpholinomethyl Resin

abx095139-1ml 1 ml
EUR 550

MP-Morpholinomethyl Resin

abx095139-200l 200 µl
EUR 262.5

silicone resin, 100 pieces/pack

CPA-100-1 each
EUR 300

Aminomethyl Polystyrene Resin

5-08191 25g Ask for price

Aminomethyl Polystyrene Resin

5-08192 100g Ask for price

Aminomethyl Polystyrene Resin

5-08193 25g Ask for price

Aminomethyl Polystyrene Resin

5-08194 100g Ask for price

MP-Diethylenetriamine resin

20-abx095136
  • Ask for price
  • Ask for price
  • 100 g
  • 25 g

MP-Diethylenetriamine Resin

abx095136-100l 100 µl
EUR 250

MP-Diethylenetriamine Resin

abx095136-1ml 1 ml Ask for price

MP-Diethylenetriamine Resin

abx095136-200l 200 µl
EUR 525

Dianion HP-20 Resin

D416514 100g
EUR 69
Description: 9052-95-3

Rink Amide-AM Resin

A6780-100000 100 g
EUR 872.4
Description: Rink Amide-AM Resin

Rink Amide-AM Resin

A6780-25000 25 g
EUR 466.8
Description: Rink Amide-AM Resin

Rink Amide-AM Resin

A6780-5000 5 g
EUR 262.8
Description: Rink Amide-AM Resin

Rink Amide-AM Resin

5-08235 25g
EUR 298.94

Rink Amide-AM Resin

5-08236 100g
EUR 898.17

Rink Amide-AM Resin

5-08237 25g
EUR 298.94

Rink Amide-AM Resin

5-08238 100g
EUR 898.17

Fmoc-Leu-Tcp Resin

5-08289 5g Ask for price

Fmoc-Leu-Tcp Resin

5-08290 25g Ask for price

Ni-NTA Agarose Resin

DS0821-25ML 1 unit
EUR 2003.45
Description: Ni-NTA Agarose Resin

Following the multitude of food microbe combinations, there are thousands of different types of fermented dairy products – yogurts, yogurt type products and various types of cheeses with proven health benefits. Among these products is the domestic Bulgarian yoghurt “Kiselo Mlyako”, whose anti-aging effect has been scientifically studied at the beginning of the 20th century. The current review overwrites the wide range of traditional fermented dairy products in the Balkan countries, which are the main source of their production.

Leave a Comment