Recent research indicated that exposure to residential vegetation (“greenery”) may be protective against cognitive decline and can support the integrity of the corresponding brain structures. However, it is still unclear about these effects, especially in less rich and middle-aged countries. In this study, we investigated the associations between greenery and neurocognitive function. We used a convenience sample of 112 middle-aged Bulgarians and two cognitive tests: the consortium for establishing a register for the neuropsychological battery of Alzheimer’s disease (CERAD-NB) and Cognitive Assessment of Montreal (MOCA). In addition, structural cerebral imaging data was available for 25 participants.

The address of the home of the participants was used to connect the cognition scores to the normalized difference vegetation index (NDVI), a measurement of the level of global vegetation of neighborhood (radii from 100 to 1000 m). The results indicated that NDVI higher was always associated with higher scores of CERAD-NB and MOCA through radial buffers and adjustment scenarios. The lower waist tower media the effect of NDVI on Cerad-NB. NDVI100-M has been positively associated with an average cortical thickness on both hemispheres, but these correlations have been marginally significant (p <0.1) after correction of the false discovery rate due to several comparisons. In conclusion, life in a greener neighborhood could be associated with better cognitive function in middle-aged Bulgarians, with central adipososity lower than partial accounting for this purpose. Provisional evidence suggests that greenery could also contribute to structural integrity in brain regions governing cognitive functions. Future research should rely on our conclusions and investigate larger and more representative population groups.

 

Criteria system for the treatment of acromegaly treatment in Bulgaria

Acromegaly is a rare endocrine disorder caused by excessive and long-time secretion of growth hormone (GH) by somatotrophasse and resulting from this overproduction of an insulin-type growth factor – 1 hormone (IGF-1) by the liver. There are few registers and clinical data quite limited on the treatment of acromegaly. The analysis of acromegaly data is rarely subject to a system of criteria for assessing the treatment of acromegaly. The novelty of this document is that it presents a case study of real practice on the results of the implementation of such a system in Bulgaria. Analysis of the case study illustrates a clinical information approach to handle thousands of records in the Bulgarian acromegaly database. The results below indicated evidence of the difficulties encountered in maintaining GH and IGF-1 levels in their reference values ​​in the treatment of acromegaly.

The current research extends the results of the evaluation by allowing semantic interoperability between acromegaly databases based on the specification of the OPENEHR. The addition of the IA 2-AB as a second immunological marker identified 94.4%, while the use of ZNT8-AB in second place identified 98.8% of cases. 24.4% presented positive thyroid antibodies and 33.8% had AIT. No relationship was found between the island and AIT antibodies. None of the patients have been positive TTG-IGA-AB. No significant correlation has been established between antibodies with different organ specificities. The purpose of the study was to evaluate the prevalence and relationship of the most frequent autoimmune diseases and self-antibodies of the autoimmune thyroid disease (AIT) and coeliac disease in Adult Bulgarian patients with short-term type 1 diabetes.

Validation of Levenson’s self-signing psychopathic scale to people dependent on the Bulgarian substance

The co-occurrence of disorders of psychopathy and substance (SADS) is associated with higher relapse rates and at an increased risk of violent criminalization. Studies on the validity of psychopathic measures in community samples and dependent people of substances (SDIS) are rare. The current study was to examine the psychometric properties of Levenson’s self-assessment psychopathy scale (LSRP) in a sample of Bulgarian SDIS and non-dependent orders. We have tested 615 participants: 106 heroin users, 91 Amphetamine users, 123 users of polysubstance and 295 commands.

The confirmation factor analyzes replicated the Tri-Factor structure of the SRPA (Egocentric, Antisocial, Calleux). The scale has demonstrated acceptable reliability and validity. SDIS has increased considerably than total controls and sub-ladders of the PSPA, indicating a good discriminant validity. Overall, the results indicate that the SRPA is a valid instrument for measuring psychopathy in the samples of the Bulgarian community. In line with the efforts to improve food practices, this comparative study assessed the objective comprehension of five different front package labels (reference inputs, multiple traffic lights, warning label, nutri-score and health Star) A sample of 1010 Bulgarian adults.

Plasmid Extraction Maxi Plus Kit (10prep), Ion Exchange
FAPMX-010	Favorgen	10 preps	EUR 201

Plasmid ExtractionMaxi Plus Kit (10prep), EndoToxinFree, Ion Exchange
FAPMX-010-EF	Favorgen	10 preps	EUR 216

Plasmid Extraction Maxi Plus Kit (20prep), Ion Exchange
FAPMX-020	Favorgen	20 preps	EUR 281

Plasmid DNA Extraction Maxi Kit (4prep), FavorFilter, Ion Exchange
FAFTE-001	Favorgen	4 preps	EUR 150

Plasmid DNA Extraction Maxi Kit (10prep), FavorFilter, Ion Exchange
FAFTE-001-1	Favorgen	10 preps	EUR 208

Plasmid DNA Extraction Midi Kit (25prep), FavorFilter, Ion Exchange
FAFTE-002	Favorgen	25 preps	EUR 245

Plasmid DNA Extraction Midi Kit (50prep), FavorFilter, Ion Exchange
FAFTE-002-1	Favorgen	50 preps	EUR 368

Plasmid DNA Extraction Midi Kit (25prep), EndoToxinFree, Ion Exchange
FAPDE-002-EF	Favorgen	25 preps	EUR 230

Plasmid DNA Extraction Maxi Kit (10prep), FavorFilter, EndotoxinFree, Ion Exchange
FAFTE-001-1-EF	Favorgen	10 preps	EUR 216

Plasmid DNA Extraction Maxi Kit (4prep), FavorFilter, EndotoxinFree, Ion Exchange
FAFTE-001-EF	Favorgen	4 preps	EUR 155

MBHA resin
20-abx095143	Abbexa	EUR 495.00 EUR 2305.00 EUR 885.00 EUR 244.00 EUR 1497.00	100 g 1 kg 250 g 25 g 500 g

Merrifield resin
20-abx095147	Abbexa	EUR 217.00 EUR 356.00 EUR 523.00	100 g 250 g 500 g

Wang resin
20-abx095148	Abbexa	EUR 314.00 EUR 523.00 EUR 885.00	100 g 250 g 500 g

AM resin
20-abx095149	Abbexa	EUR 314.00 EUR 592.00 EUR 885.00	100 g 250 g 500 g

Wang Resin
A6776-100000	ApexBio	100 g	EUR 200
Description: Wang Resin

Wang Resin
A6776-25000	ApexBio	25 g	EUR 125
Description: Wang Resin

GST-Sefinose Resin
BSP031	Bio Basic	5ml	EUR 145.7

GST-Sefinose Resin
BSP031-1	Bio Basic	25ml	EUR 415.4

MP-EDC resin
20-abx095129	Abbexa	EUR 1052.00 EUR 439.00 EUR 217.00	100 g 25 g 5 g

MP-TEMPO resin
20-abx095130	Abbexa	EUR 1052.00 EUR 439.00 EUR 217.00	100 g 25 g 5 g

MP-Aminomethyl resin
20-abx095132	Abbexa	EUR 328.00 EUR 189.00	100 g 25 g

MP-Acetylacetone resin
20-abx095133	Abbexa	EUR 439.00 EUR 230.00	100 g 25 g

MP-Piperazinomethyl resin
20-abx095134	Abbexa	EUR 439.00 EUR 230.00	100 g 25 g

MP-Diethylenetriamine resin
20-abx095136	Abbexa	EUR 453.00 EUR 230.00	100 g 25 g

MP-Carbonate resin
20-abx095138	Abbexa	EUR 467.00 EUR 244.00	100 g 25 g

MP-Morpholinomethyl resin
20-abx095139	Abbexa	EUR 467.00 EUR 244.00	100 g 25 g

MP-Thiosulfate resin
20-abx095140	Abbexa	EUR 467.00 EUR 244.00	100 g 25 g

MP-Mercaptomethyl resin
abx095141-100g	Abbexa	100 g	EUR 509

MP-TMT resin
20-abx095142	Abbexa	EUR 578.00 EUR 272.00	100 g 25 g

Ni-NTA Resin
20-abx098108	Abbexa	EUR 509.00 EUR 244.00	25 ml 5 ml

Ni-IDA Resin
20-abx098109	Abbexa	EUR 453.00 EUR 230.00	25 ml 5 ml

Protein A Resin
abx098111-5ml	Abbexa	5 ml	EUR 398

Protein G Resin
abx098112-5ml	Abbexa	5 ml	EUR 439

Aminomethyl Polystyrene Resin
5-08191	CHI Scientific	25g	Ask for price

Aminomethyl Polystyrene Resin
5-08192	CHI Scientific	100g	Ask for price

Aminomethyl Polystyrene Resin
5-08193	CHI Scientific	25g	Ask for price

Aminomethyl Polystyrene Resin
5-08194	CHI Scientific	100g	Ask for price

Rink Amide Resin
A6576-100000	ApexBio	100 g	EUR 947
Description: Rink resin is originally developed for SPS of peptide amides. Now the scope of its application is extended from carboxylic amides to the immobilization of amines, substituted amides.

Rink Amide Resin
A6576-25000	ApexBio	25 g	EUR 299
Description: Rink resin is originally developed for SPS of peptide amides. Now the scope of its application is extended from carboxylic amides to the immobilization of amines, substituted amides.

DHP HM Resin
A6789-100000	ApexBio	100 g	EUR 514
Description: DHP HM Resin

DHP HM Resin
A6789-25000	ApexBio	25 g	EUR 203
Description: DHP HM Resin

Glutathione Agarose Resin
4B-GLU-10	ABTBeads	10 ml	EUR 173

Glutathione Agarose Resin
4B-GLU-100	ABTBeads	100 ml	EUR 996

Biotin Agarose Resin
4BCL-BI-10	ABTBeads	10 ml	EUR 411

Biotin Agarose Resin
4BCL-BI-5	ABTBeads	5 ml	EUR 235

M2 ion channel blocker
HY-75867	MedChemExpress	100mg	EUR 317

Protein A-Agarose Resin
55000	AAT Bioquest	1 mL	EUR 132

Protein A-Agarose Resin
55005	AAT Bioquest	5 mL	EUR 306

Protein G Agarose Resin
SF022-PG	Bio Basic	5ml	EUR 775

Protein A Agarose Resin
BSP095-7	Bio Basic	1ml	EUR 93.5

Protein A Agarose Resin
BSP095-8	Bio Basic	5ml	EUR 245.75

Protein A Sefinose Resin
BSP096-25	Bio Basic	12.5ml	EUR 702.5

Protein A Sefinose Resin
BSP096-5	Bio Basic	2.5ml	EUR 193.55

Fmoc-Gly-Wang resin
20-abx095122	Abbexa	EUR 551.00 EUR 258.00	100 g 25 g

MP-Sulfonic acid resin
20-abx095135	Abbexa	EUR 439.00 EUR 230.00	100 g 25 g

2-Chlorotrityl Chloride resin
20-abx095137	Abbexa	EUR 467.00 EUR 899.00 EUR 230.00 EUR 1609.00	100 g 250 g 25 g 500 g

Rink Amide AM resin
20-abx095146	Abbexa	EUR 801.00 EUR 4156.00 EUR 1455.00 EUR 328.00 EUR 2249.00	100 g 1 kg 250 g 25 g 500 g

Fmoc-Ala-Wang resin
5-07835	CHI Scientific	5g	Ask for price

Fmoc-Ala-Wang resin
5-07836	CHI Scientific	25g	Ask for price

Fmoc-Acp-Wang resin
5-07841	CHI Scientific	5g	Ask for price

Fmoc-Acp-Wang resin
5-07842	CHI Scientific	25g	Ask for price

Fmoc-Cha-Wang Resin
5-07863	CHI Scientific	5g	Ask for price

Fmoc-Cha-Wang Resin
5-07864	CHI Scientific	25g	Ask for price

Fmoc-Cit-Wang resin
5-07867	CHI Scientific	5g	Ask for price

Fmoc-Cit-Wang resin
5-07868	CHI Scientific	25g	Ask for price

Fmoc-Gly-Wang resin
5-07891	CHI Scientific	5g	Ask for price

Fmoc-Gly-Wang resin
5-07892	CHI Scientific	25g	Ask for price

Fmoc-Gly-Wang resin
5-07893	CHI Scientific	5g	Ask for price

Fmoc-Gly-Wang resin
5-07894	CHI Scientific	25g	Ask for price

Fmoc-Ile-Wang resin
5-07899	CHI Scientific	5g	Ask for price

Fmoc-Ile-Wang resin
5-07900	CHI Scientific	25g	Ask for price

Fmoc-Leu-Wang resin
5-07903	CHI Scientific	5g	Ask for price

Fmoc-Leu-Wang resin
5-07904	CHI Scientific	25g	Ask for price

Fmoc-Leu-Wang resin
5-07905	CHI Scientific	5g	Ask for price

Fmoc-Leu-Wang resin
5-07906	CHI Scientific	25g	Ask for price

Fmoc-Lys-Wang resin
5-07907	CHI Scientific	5g	Ask for price

Fmoc-Lys-Wang resin
5-07908	CHI Scientific	25g	Ask for price

Fmoc-Met-Wang resin
5-07923	CHI Scientific	5g	Ask for price

Fmoc-Met-Wang resin
5-07924	CHI Scientific	25g	Ask for price

Fmoc-Phe-Wang resin
5-07929	CHI Scientific	5g	Ask for price

Fmoc-Phe-Wang resin
5-07930	CHI Scientific	25g	Ask for price

Fmoc-Phe-Wang resin
5-07931	CHI Scientific	5g	Ask for price

Fmoc-Phe-Wang resin
5-07932	CHI Scientific	25g	Ask for price

Fmoc-Pro-Wang resin
5-07947	CHI Scientific	5g	Ask for price

Fmoc-Pro-Wang resin
5-07948	CHI Scientific	25g	Ask for price

Fmoc-Pro-Wang resin
5-07949	CHI Scientific	5g	Ask for price

Fmoc-Pro-Wang resin
5-07950	CHI Scientific	25g	Ask for price

Fmoc-Tle-Wang Resin
5-07965	CHI Scientific	5g	Ask for price

Fmoc-Tle-Wang Resin
5-07966	CHI Scientific	25g	Ask for price

Fmoc-Thr-Wang resin
5-07967	CHI Scientific	5g	Ask for price

Fmoc-Thr-Wang resin
5-07968	CHI Scientific	25g	Ask for price

Fmoc-Trp-Wang resin
5-07975	CHI Scientific	5g	Ask for price

Fmoc-Trp-Wang resin
5-07976	CHI Scientific	25g	Ask for price

Fmoc-Val-Wang resin
5-07989	CHI Scientific	5g	Ask for price

Fmoc-Val-Wang resin
5-07990	CHI Scientific	25g	Ask for price

2-Chlorotrityl Chloride Resin
5-08183	CHI Scientific	25g	Ask for price

2-Chlorotrityl Chloride Resin
5-08184	CHI Scientific	100g	Ask for price

2-Chlorotrityl Chloride Resin
5-08185	CHI Scientific	25g	Ask for price

2-Chlorotrityl Chloride Resin
5-08186	CHI Scientific	100g	Ask for price

Fmoc-Leu-Tcp Resin
5-08289	CHI Scientific	5g	Ask for price

Fmoc-Leu-Tcp Resin
5-08290	CHI Scientific	25g	Ask for price

Rink Amide-AM Resin
A6780-100000	ApexBio	100 g	EUR 727
Description: Rink Amide-AM Resin

Rink Amide-AM Resin
A6780-25000	ApexBio	25 g	EUR 389
Description: Rink Amide-AM Resin

Rink Amide-AM Resin
A6780-5000	ApexBio	5 g	EUR 219
Description: Rink Amide-AM Resin

2-Chlorotrityl Chloride Resin
A6791-100000	ApexBio	100 g	EUR 328
Description: 2-Chlorotrityl Chloride Resin

2-Chlorotrityl Chloride Resin
A6791-25000	ApexBio	25 g	EUR 142
Description: 2-Chlorotrityl Chloride Resin

Fmoc-Phe-Wang resin
A6831-25000	ApexBio	25 g	EUR 205
Description: Fmoc-Phe-Wang resin

Fmoc-Phe-Wang resin
A6831-5000	ApexBio	5 g	EUR 87
Description: Fmoc-Phe-Wang resin

Fmoc-Ile-Wang resin
A6836-25000	ApexBio	25 g	EUR 205
Description: Fmoc-Ile-Wang resin

Fmoc-Ile-Wang resin
A6836-5000	ApexBio	5 g	EUR 87
Description: Fmoc-Ile-Wang resin

Fmoc-Gly-Wang resin
A6839-25000	ApexBio	25 g	EUR 205
Description: Fmoc-Gly-Wang resin

Fmoc-Gly-Wang resin
A6839-5000	ApexBio	5 g	EUR 87
Description: Fmoc-Gly-Wang resin

Protein L Agarose Resin
4BCLPL-10	ABTBeads	10 ml	EUR 393

Protein L Agarose Resin
4BCLPL-2	ABTBeads	2 ml	EUR 197

Protein L Agarose Resin
4BCLPL-5	ABTBeads	5 ml	EUR 284

Nickel NTA Agarose Resin
6BCL-NTANi-100	ABTBeads	100 ml	EUR 651

Nickel NTA Agarose Resin
6BCL-NTANi-25	ABTBeads	25 ml	EUR 217

Nickel NTA Agarose Resin
6BCL-NTANi-500	ABTBeads	500 ml	EUR 2584

Protein A Agarose Resin
PA09-100	ABTBeads	100 ml	EUR 2094

Protein A Agarose Resin
PA09-25	ABTBeads	25 ml	EUR 925

Protein A Agarose Resin
PA09-5	ABTBeads	5 ml	EUR 291

Streptavidin 6HC Agarose Resin
STV6HC-10	ABTBeads	10 ml	EUR 399

Streptavidin 6HC Agarose Resin
STV6HC-20	ABTBeads	20 ml	EUR 685

Streptavidin 6HC Agarose Resin
STV6HC-5	ABTBeads	5 ml	EUR 237

ph/mv/ion/o2 module
D291	Consort	ea	EUR 649

Fast Ion Plasmid Midi Kit
FYG002-25P	Yeastern Biotech	25 Preps	Ask for price

Fast Ion Plasmid Maxi Kit
FYG004-10P	Yeastern Biotech	10 Preps	Ask for price

Fast Ion Plasmid Maxi Kit
FYG004-25P	Yeastern Biotech	25 Preps	Ask for price

DiscoveryProbe? Ion Channel Compound Library
L1030-.1	ApexBio	100 uL/well(10 mM solution)	EUR 5560

DiscoveryProbe? Ion Channel Compound Library
L1030-.25	ApexBio	250 uL/well(10 mM solution)	EUR 9886

DiscoveryProbe? Ion Channel Compound Library
L1030-5	ApexBio	5 mg/well	EUR 12902

Boc-His(Tos)-Merrifield Resin
20-abx186052	Abbexa	EUR 773.00 EUR 384.00	25 g 5 g

Fmoc-L-Ala-Wang resin
20-abx095121	Abbexa	EUR 551.00 EUR 258.00	100 g 25 g

The objective understanding has been evaluated by comparing the results of two nutrition quality classification tasks (with and without FOPL) in a randomized online experience presenting three food categories (pizza, cakes, breakfast cereals). Multivarioocial ordinal logistic regression models in food categories and through foods were fit. Nutri-score, which is a summary, interpretative, polychromatic FOPL, appeared as the most effective model in the Bulgarian context, with the potential to help consumers better understand the nutritional quality of food. The conclusions are of particular interest to public health decision-makers in the region and throughout Europe, the debate on a FOPL model at EU-wide level continues to gather momentum.